History. Phenylephrine and PseudoephedrinePhenylephrine and pseudoephedrine are both decongestants. Historically, pseudoephedrine has been the more commonly used decongestant in many nonprescription cold and allergy medications. However, pseudoephedrine is also a key ingredient in making methamphetamine, a highly addictive illegal stimulant. Federal law now requires all …
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